Dose Optimization and Targeting Strategies of Anti-Infective Agents
نویسندگان
چکیده
Most drugs are currently developed, approved and marketed based on their effect the majority of population [...]
منابع مشابه
Limited-sampling strategies for anti-infective agents: systematic review.
BACKGROUND Area under the concentration-time curve (AUC) is a pharmacokinetic parameter that represents overall exposure to a drug. For selected anti-infective agents, pharmacokinetic-pharmacodynamic parameters, such as AUC/MIC (where MIC is the minimal inhibitory concentration), have been correlated with outcome in a few studies. A limited-sampling strategy may be used to estimate pharmacokine...
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1 Centre National de Référence des Francisella, Institut de Biologie et Pathologie, Centre Hospitalier Universitaire de Grenoble, Grenoble, France 2 Laboratoire Adaptation et Pathogénie des Microorganismes, Université Joseph Fourier – Grenoble 1, Grenoble, France 3 Laboratoire Adaptation et Pathogénie des Microorganismes, CNRS/UJF, UMR 5163, Grenoble, France *Correspondence: mmaurin@chu-grenobl...
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ژورنال
عنوان ژورنال: Pharmaceutics
سال: 2023
ISSN: ['1999-4923']
DOI: https://doi.org/10.3390/pharmaceutics15071870